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wildmoor
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Location: Oldham, UK
Joined: Oct 2006
Posts: 1,299
Female 
 
06-03-2010, 07:14 PM

Anal Furunculosis genetic test available - GSDs

http://www.genoscoper.com/in_english...t_information/

http://www.genoscoper.com/@Bin/12140...order+form.pdf

Price €60
Sample type required: blood or cheek swab

The results of the test are reported as follows:
NORMAL: Do not carry the risk allele DRB*00101 and has therefore no increased risk of developing anal furunculosis.
CARRIER: (Heterozygote): Carries one copy of the DRB*00101 allele and because of the dominant inheritance has therefore a risk 5 times higher of developing anal furunculosis. Carrier can also transfer the defect to approximately 50% of its progeny.
AFFECTED: (Homozygote): Carries two copies of the DRB*00101 allele and has therefore a risk 5 times higher of developing perianal fistula than a normal dog. Sick homozygote usually develops the disease at younger age than a heterozygote. It will also transfer the gene defect to all of its progeny.
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Tupacs2legs
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Location: london.uk
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06-03-2010, 07:17 PM
thanks for this...i will ring a client on monday that wishes to breed their GSD
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wildmoor
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06-03-2010, 10:50 PM
I take it you are saying it as been treated for AF but the owner intends breeding from it , also inform them that under legislation they can taken to court for cost incurred by potential puppy owners if they also go onto develop it.
Castrating affected males helps in reducing outbreaks, maybe you can persuade them it will be cheaper in the long run to not breed lol
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Tupacs2legs
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Location: london.uk
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Posts: 8,012
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06-03-2010, 10:55 PM
Originally Posted by wildmoor View Post
I take it you are saying it as been treated for AF but the owner intends breeding from it , also inform them that under legislation they can taken to court for cost incurred by potential puppy owners if they also go onto develop it.
Castrating affected males helps in reducing outbreaks, maybe you can persuade them it will be cheaper in the long run to not breed lol
im working on it
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